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Mice live longer when inflammation-boosting protein is blocked

Humans also have the protein, called IL-11, offering hope for a future longevity treatment.
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  1. Heidi Ledford
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A protein that promotes inflammation could hold the key to a longer, healthier life. Blocking the protein, called IL-11, in middle-aged mice boosted metabolism, reduced frailty and increased lifespan by about 25%.

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Nature 631, 716-717 (2024)

doi: https://doi.org/10.1038/d41586-024-02298-5

References

  1. Widjaja, A. A. et al. Nature https://doi.org/10.1038/s41586-024-07701-9 (2024).

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  2. Cook, S.A. & Schafer, S. Annu. Rev. Med. 71, 263–276 (2020).

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